A grippi virusi / B grippi virusi
Mahsulot nomi
HWTS-RT176-Muzlatib quritilgan A grippi virusi/B grippi virusi nuklein kislotasini aniqlash to'plami (floresan PZR)
Mahsulotni tasdiqlash
IVDR
Epidemiologiya
NP va M genlari orasidagi antigenik farqlarga ko'ra, gripp viruslarito'rt turga bo'lish mumkin: A grippi virusi (IFV A), B grippi virusi (IFV B),gripp C virusi (IFV C) va gripp D virusi (IFV D) [1]. Gripp A virusi uchun,u ko'plab xostlar va murakkab serotiplarga ega va xostlar orasida tarqalishi mumkingenetik rekombinatsiya va adaptiv mutatsiyalar. Odamlarda uzoq muddatli immunitet yo'qA grippi virusi, shuning uchun har qanday yoshdagi odamlar odatda moyil. A grippi virusigripp pandemiyalarini keltirib chiqaradigan eng asosiy patogenlardir [2]. B grippi virusi uchun,u asosan kichik hududlarda tarqaladi va hozirda hech qanday kichik tipga ega emas. InsonInfektsiyalar asosan B/Yamagata yoki B/Victoria gripp viruslari tufayli yuzaga keladinasl-nasab. 15 mamlakatda oylik tasdiqlangan gripp holatlari orasidaOsiyo-Tinch okeani mintaqasida B grippi virusini tashxislash darajasi 0 dan 92% gacha[3]. A grippi virusidan farqli o'laroq, bolalar va boshqa ayrim odamlar guruhlarikeksa yoshdagilar, asoratlarni osonlikcha keltirib chiqarishi mumkin bo'lgan B grippi virusiga moyil bo'ladilar,jamiyat uchun A grippi virusidan ham ko'proq yuk tug'diradi[4].Salbiy natija IFV A/B infeksiyasini istisno qilmaydi va uni quyidagi hollarda ishlatmaslik kerak:tashxis qo'yish, davolash yoki boshqa boshqaruv qarorlari uchun yagona asos. IjobiyNatija IFVdan tashqari bakterial infeksiya yoki boshqa virusli qo'shma infeksiyani istisno qilmaydi.A/B virusi.
Texnik parametrlar
| Saqlash | 2-28℃ |
| Yaroqlilik muddati | 12 oy |
| Namuna turi | inson orofaringeal tampon, nazofaringeal tampon |
| Ct | ≤38 |
| CV | <5.0% |
| LoD | 200 nusxa/ml yoki 0,05TCID50/ml |
| O'ziga xoslik | O'zaro reaktivlik: To'plam va Bokavirus, Respirator sinsitial virus B turi, Herpes simplex virusi 1 turi, Enterovirus, Adenovirus (1-tur), Adenovirus (3-tur), Adenovirus (7-tur), SARS-CoV, Adenovirus (1-tur), Adenovirus (3-tur), Adenovirus (7-tur), SARS-CoV, Norovirus, Streptococcus pneumoniae, Legionella, Bordetella pertussis, Neisseria gonorrhoeae, Aspergillus fumigatus, Moraxella catarrhalis, Rhinovirus, Parainfluenza virusi (1-tur), Parainfluenza virusi (3-tur), Parainfluenza virusi (2-tur), Varicella-zoster virusi, Qizamiq virusi, Inson koronaviruslari, MERS-CoV, Chlamydia pneumoniae, Klebsiella pneumoniae, Pneumocystis jirovecii, Staphylococcus aureus, Candida o'rtasida o'zaro reaktivlik yo'q. albicans, Cryptococcus neoformans, Lactobacillus, Sitomegalovirus, Epstein-Barr virusi, Tepki virusi, Odam metapnevmovirusi (A1), Odam metapnevmovirusi (B2), Yangi koronavirus 2019-nCoV, Rotavirus, Mycoplasma pneumoniae, Streptococcus pyogenes, Haemophilus influenzae, Mycobacterium tuberculosis, Candida glabrata, Streptococcus salivarius, Corynebacterium, A grippi virusi, B grippi virusi, Inson genomik DNKsi |
| Amaldagi asboblar | I toifa: Amaliy Biosistemalar 7500 Real-Time PCR tizimlari, SLAN-96PReal vaqt rejimida PCR tizimlari (Hongshi Medical Technology Co., Ltd.). II turdagi sinov: Jiangsu Macro tomonidan ishlab chiqarilgan EudemonTM AIO800 (HWTS-EQ007) & Micro-Test Med-Tech Co., Ltd. |
Ish oqimi
I toifa: An'anaviy PCR tizimida
II toifa: EudemondaTMAIO800
Reaktivlar/asboblar kerak, lekin taqdim etilmaydi
1) RNK ekstraksiya to'plami: Makro va makro va mikro-test virusli DNK/RNK to'plami(HWTS-3017) (makro va mikro-test avtomatik yadrosi bilan ishlatilishi mumkin)Kislota ekstraktori (HWTS-EQ011)) Jiangsu Macro & Micro-Test Med-Tech Co. tomonidan ishlab chiqarilgan.Ltd., Makro va Mikro-Test Virusli DNK/RNK to'plami (HWTS-3017-8) (bilan ishlatiladi)Jiangsu Macro & Micro-Test Med-Tech tomonidan ishlab chiqarilgan EudemonTM AIO800 (HWTS-EQ007)Co., Ltd.
2) Namunalarni saqlash yechimi: Viruslarni namunalash to'plami (JXZZ20182400236) tomonidanYocon Biology (Pekin) Co., Ltd., UTM® Universal Transport Medium™(GXB20191277) Copan Italia SpA tomonidan, Makro va Mikro-sinov namunalarini yig'ish,Jiangsu Macro & Micro-Test Med-Tech tomonidan ishlab chiqarilgan pochta va yetkazib berish to'plami (HWTS-3002)Co., Ltd.
Sarf materiallari quyidagilarni talab qiladi, ammo ta'minlamaydi:DNase/RNasesiz uchlar, bir martalik qo'lqoplar,DNase/RNasesiz EP naychalari.
